@inproceedings {24567,
	title = {Optimization of a Spatially Varying Cardiac Contraction parameter using the Adjoint Method},
	journal = {FEniCS{\textquoteright}16},
	year = {2016},
	abstract = {A cardiac computational model is constrained using clinical measurements such as pressure, volume and regional strain. The problem is formulated as a PDE-constrained optimisation problem where the objective functional represents the misfit between measured and simulated data. The control parameter for the active phase is a spatially varying contraction parameter defined at every vertex in the mesh. This makes gradient calculations using the adjoint approach computationally advantageous over standard finite difference approximations.},
	keywords = {Adjoint Method, Cardiac Mechanics, parameter estimation, PDE-constrained optimization},
	author = {Finsberg, Henrik and Balaban, Gabriel and Marie E. {Rognes} and Sundnes, Joakim and Wall, Samuel}
}
