@article {28044,
	title = {T cell receptor repertoire as a potential diagnostic marker for celiac disease},
	journal = {Clinical Immunology},
	volume = {222},
	year = {2021},
	month = {01/2021},
	publisher = {Elsevier},
	abstract = {An individual{\textquoteright}s T cell repertoire is skewed towards some specificities as a result of past antigen exposure and subsequent clonal expansion. Identifying T cell receptor signatures associated with a disease is challenging due to the overall complexity of antigens and polymorphic HLA allotypes. In celiac disease, the antigen epitopes are well characterised and the specific HLA-DQ2-restricted T-cell repertoire associated with the disease has been explored in depth. By investigating T cell receptor repertoires of unsorted lamina propria T cells from 15 individuals, we provide the first proof-of-concept study showing that it could be possible to infer disease state by matching against a priori known disease-associated T cell receptor sequences.},
	author = {Yao, Ying and Zia, Asima and Ralf Stefan {Neumann} and Pavlovic, Milena and Balaban, Gabriel and Knut EA {Lundin} and Geir Kjetil {Sandve} and Qiao, Shuo-Wang}
}
