@article {43096,
	title = {Human brain solute transport quantified by glymphatic MRI-informed biophysics during sleep and sleep deprivation},
	journal = {Fluids and Barriers of the Central Nervous System},
	year = {2023},
	month = {08/2023},
	publisher = {Springer Nature},
	abstract = {Human brain homeostasis requires carefully regulated transport of nutrients and waste, but its governing mechanisms are hard to quantify. By combining multi-modal gMRI data over 48 hours with high-fidelity inverse computational modelling, we here identify several potential transport mechanisms that best explain the clinical observations. Our findings support the combined roles of local, vascular and glymphatic-type clearance pathways within human brain tissue with tissue flow velocities on the order of $\mu$m/min, local clearance rates at the order of 10**(-3)/min, and\&nbsp;enhanced diffusion by a factor 3.5, in sleeping and sleep-deprived subjects. Reduced advection fully explains reduced tracer clearance after sleep-deprivation, supporting the role of sleep and sleep deprivation on human brain clearance.},
	doi = {https://doi.org/10.1101/2023.01.01.522190},
	author = {Vinje, Vegard and Zapf, Bastian and Ringstad, Geir and Per Kristian {Eide} and Marie E. {Rognes} and Mardal, Kent-Andre}
}
@article {25781,
	title = {Comparison of phase-contrast MR and flow simulations for the study of CSF dynamics in the cervical spine},
	journal = {The Neuroradiology Journal},
	volume = {31},
	year = {2018},
	pages = {292-298},
	publisher = { SAGE Publications},
	doi = {10.1177/1971400918759812},
	author = {Erika Kristina {Lindstr{\o}m} and Schreiner, Jakob and Ringstad, Geir and Haughton, Victor and Per Kristian {Eide} and Mardal, Kent-Andre}
}
@misc {26046,
	title = {Respiratory influence on intracranial pressure gradients and aqueductal flow in normal pressure hydrocephalus},
	year = {2018},
	month = {07/2018},
	type = {Poster Presentation at World Congress of Biomechanics},
	address = {Dublin, Ireland},
	abstract = {Phase contrast MRI does not take into account the role of respiration on cerebrospinal fluid (CSF) flow. We used in vivo pressure measurements from two locations in the intracranial space to calculate a pulsatile pressure gradient. This pressure data was used as input to an idealized model of the aqueduct to calculate CSF flow. We found the cardiac and respiratory cycle to contribute equally to CSF flow. The total flow volume was dominated by respiration, and all subjects showed variability in pressure gradients over time resulting also in variability in CSF flow.},
	url = {https://app.oxfordabstracts.com/stages/123/programme-builder/submission/20200?backHref=/events/123/programme-builder/view/sort/topic\&view=published},
	author = {Vinje, Vegard and Ringstad, Geir and Marie E. {Rognes} and Per Kristian {Eide} and Mardal, Kent-Andre}
}
@article {24810,
	title = {Non-invasive Assessment of Pulsatile Intracranial Pressure with Phase-Contrast Magnetic Resonance Imaging},
	journal = {PLoS ONE},
	volume = {12},
	year = {2017},
	pages = {e0188896},
	publisher = {PLOS ONE},
	doi = {10.1371/journal.pone.0188896},
	author = {Ringstad, Geir and Lindstr{\o}m, Erika and Svein Are {Vatnehol} and Mardal, Kent-Andre and Emblem, Kyrre and Per Kristian {Eide}}
}
@article {24822,
	title = {Association of pulse pressure gradient across cranio-cervical junction as derived from phase-contrast magnetic resonance imaging and invasively measured pulsatile intracranial pressure   in symptomatic patients with  Chiari malformation type 1},
	journal = {Acta Neurochirurgica},
	volume = {158},
	year = {2016},
	publisher = {Springer},
	author = {Fric, Radek and Erika Kristina {Lindstr{\o}m} and Ringstad, Geir and Mardal, Kent-Andre and Per Kristian {Eide}}
}
@article {24806,
	title = {Direct numerical simulations of transitional hydrodynamics of the cerebrospinal fluid in Chiari I malformation {\textendash} the role of cranio-vertebral junction},
	journal = {International Journal for Numerical Methods in Biomedical Engineering},
	year = {2016},
	publisher = {John Wiley \& Sons},
	author = {Jain, Kartik and Ringstad, Geir and Eide, Per-Kristian and Mardal, Kent-Andre}
}
@misc {csf-symp,
	title = {On the complexity of the Cerebrospinal fluid flow in the upper spinal column {\textendash} is the assumption of laminar flow appropriate?},
	howpublished = {Cerebrospinal Fluid Dynamics Society Meeting, Amiens},
	year = {2015},
	type = {Invited talk},
	author = {Mardal, Kent-Andre and Jain, Kartik and St{\o}verud, Karen-Helene and Ringstad, Geir and Per Kristian {Eide}}
}
@misc {Simula.simula.2918,
	title = {CSF Flow at Foramen Magnum},
	howpublished = {International Hydrocephalus Imaging Working Group,Montreal, Canada},
	year = {2014},
	author = {Mardal, Kent-Andre and St{\o}verud, Karen-Helene and Ringstad, Geir and Per Kristian {Eide}}
}
