@article {Simula.simula.1466,
	title = {Computing Ischemic Regions in the Heart With the Bidomain Model; First Steps Towards Validation},
	journal = {IEEE Transactions on Medical Imaging},
	volume = {32},
	number = {6},
	year = {2013},
	pages = {1085-1096},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per}
}
@inproceedings {Simula.simula.1544,
	title = {On the Use of the Bidomain Model for Computing the Position and Size of Ischemic Regions; a Validation Study},
	journal = {Computing in Cardiology},
	volume = {39},
	year = {2012},
	pages = {449-452},
	publisher = {Computing in Cardiology},
	type = {Conference},
	keywords = {Conference},
	author = {Ola Marius {Lysaker} and Nielsen, Bj{\o}rn Fredrik and Gr{\o}ttum, Per},
	editor = {Murray, Alan}
}
@misc {Simula.sc.856,
	title = {Theoretical and Practical Aspects of the Inverse Ischemia Problem},
	howpublished = {Presented at Karlsruhe Institute of Technology, Germany},
	year = {2010},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per}
}
@inbook {Simula.SC.482,
	title = {Can ECG Recordings and Mathematics Tell the Condition of Your Heart?},
	booktitle = {Simula Research Laboratory - by thinking constantly about it},
	year = {2009},
	pages = {287-319},
	publisher = {Springer},
	organization = {Springer},
	chapter = {22},
	address = {Heidelberg},
	isbn = {978-3-642-01156-6},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Mardal, Kent-Andre and Tveito, Aslak and Tarrou, Christian and Haugaa, Kristina and Abildgaard, Andreas and Jan Gunnar {Fjeld}},
	editor = {Tveito, Aslak and Are Magnus {Bruaset} and Lysne, Olav}
}
@misc {Simula.SC.638,
	title = {The Inverse Ischemia Problem; Mathematical Models and Validation},
	howpublished = {Presented at the Applied Inverse Problems conference, Vienna, Austria},
	year = {2009},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Haugaa, Kristina and Jan Gunnar {Fjeld} and Abildgaard, Andreas}
}
@inproceedings {Simula.SC.484,
	title = {Mathematical Based Imaging of Regional Ischemia},
	journal = {World Congress on Medical Physics and Biomedical Engineering},
	volume = {25},
	number = {2},
	year = {2009},
	pages = {98-101},
	publisher = {Springer},
	type = {Conference},
	abstract = {Abstract-The Inverse Problems Project at Simula Research Laboratory has during the last five years analyzed and solved inverse problems arising in connection with ECG (electrocardiogram) recordings. In this paper we discuss a framework involving multi-channel ECG data along with advanced mathematical models for identifying ischemic regions in the human heart. More precisely, the ischemic region is identified by minimizing an objective function measuring the difference between recorded and simulated multi-channel ECG signals. Based on this, the functional condition of the heart is visualized in terms of an image.},
	isbn = {978-3-642-03878-5},
	author = {Ola Marius {Lysaker} and Nielsen, Bj{\o}rn Fredrik and Gr{\o}ttum, Per and Haugaa, Kristina and Jan Gunnar {Fjeld} and Abildgaard, Andreas},
	editor = {D{\"o}ssel, Olaf and Wolfgang C. {Schlegel}}
}
@misc {Simula.sc.690,
	title = {Modelling, Mathematical Properties and Validation of the Inverse Ischemia Problem},
	howpublished = {Presented at the Bidomain Workshop, Graz, Austria},
	year = {2009},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Tveito, Aslak and Haugaa, Kristina and Abildgaard, Andreas and Jan Gunnar {Fjeld} and Burger, Martin}
}
@misc {Simula.SC.118,
	title = {Computer Simulations for Identifying Ischemic Heart Disease; a Validation Study},
	howpublished = {Presented at the BBG-MedViz seminar at the Department of Mathematics, University of Bergen},
	year = {2008},
	author = {Ola Marius {Lysaker} and Nielsen, Bj{\o}rn Fredrik and Gr{\o}ttum, Per and Abildgaard, Andreas and Fjeld, Jan and Haugaa, Kristina}
}
@misc {Simula.SC.126,
	title = {The Inverse Problem of Identifying Ischemic Heart Disease},
	howpublished = {Presented at the annual meeting of European Cardiac Simulation Group, Bologna, Italy},
	year = {2008},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Tveito, Aslak and Abildgaard, Andreas and Jan Gunnar {Fjeld} and Haugaa, Kristina}
}
@misc {Simula.SC.109,
	title = {Theoretical and Practical Aspects of the Inverse Problem of Electrocardiography},
	howpublished = {Presented at Institut f{\"u}r Mathematik und Wissenschaftliches Rechnen, Karl Franzes Universit{\"a}t in Graz, Austria. Also presented at Institut f{\"u}r Numerische und Angewandte Mathematik, Westf{\"a}lische Wilhelms-Universit{\"a}t M{\"u}nster, Germany},
	year = {2008},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Tveito, Aslak and Abildgaard, Andreas and Jan Gunnar {Fjeld} and Haugaa, Kristina}
}
@misc {Simula.SC.120,
	title = {Theoretical and Practical Aspects of the Inverse Problem of Electrocardiography},
	howpublished = {Presented at the Fourth International Conference Inverse Problems: Modeling and Simulation, Turkey},
	year = {2008},
	author = {Ola Marius {Lysaker} and Nielsen, Bj{\o}rn Fredrik and Gr{\o}ttum, Per and Abildgaard, Andreas and Fjeld, Jan and Haugaa, Kristina}
}
@misc {Simula.SC.98,
	title = {On the Use of Computer Simulations for Identifying Ischemic Heart Disease; Theoretical and Practical Aspects},
	howpublished = {Presented at the workshop Mathematics in Medicine/Biology, Centre of Mathematics for Applications, Department of Mathematics, University of Oslo},
	year = {2008},
	author = {Nielsen, Bj{\o}rn Fredrik and Ola Marius {Lysaker} and Gr{\o}ttum, Per and Tveito, Aslak and Abildgaard, Andreas and Jan Gunnar {Fjeld} and Haugaa, Kristina}
}
@article {Lines.2006.1,
	title = {Contribution of the Na/Ca Exchanger to Rapid Ca Release in Cardiomyocytes},
	journal = {Biophysical Journal},
	volume = {91},
	number = {3},
	year = {2006},
	pages = {779-792},
	abstract = {Trigger Ca is considered to be the Ca current through the L-type Ca channel (LTCC) that causes release of Ca from the sarcoplasmic reticulum (SR). However, cell contraction also occurs in the absence of the LTCC current (ICa). In this paper we investigate the contribution of the Na/Ca -exchanger (NCX) to the trigger Ca. Experimental data from rat cardiomyocytes using confocal microscopy indicating that inhibition of reverse mode Na/Ca -exchange delays the Ca transient by 3-4 ms, served as a basis for the mathematical model. A detailed computational model of the dyadic cleft (fuzzy space) is presented where the diffusion of both Na and Ca is taken into account. Ionic channels are included at discrete locations, making it possible to study the effect of channel position and colocalization. The simulations indicate that if a Na channel is present in the fuzzy space, the NCX is able to bring enough Ca into the cell to affect the timing of release. However, this critically depends on channel placement and local diffusion properties. With fuzzy space diffusion in the order of 1\% compared to bulk diffusion, triggering through LTCC alone was 3-4 ms slower than with the presence of a Na channel and NCX.},
	author = {Glenn T. {Lines} and J{\o}rn Bodvar {Sande} and William E. {Louch} and Halvor K. {M{\o}rk} and Gr{\o}ttum, Per and Ole M. {Sejersted}}
}
