@inbook {Simula.simula.2290,
	title = {Calcium Signaling in Cardiomyocyte Models With Realistic Geometries (7th Edition)},
	booktitle = {Cardiac Electrophysiology: From Cell to Bedside},
	year = {2016},
	publisher = {Elsevier Science},
	organization = {Elsevier Science},
	edition = {7},
	chapter = {33},
	isbn = {9781455728565},
	author = {Andrew G {Edwards} and Johan Elon {Hake} and Anushka P. {Michailova} and Hoshijima, Masahiko and Andrew D. {McCulloch}},
	editor = {Zipes, Douglas and Jalife, Jose}
}
@inproceedings {23356,
	title = {A Markov-State Model for the Regulation of the Sarcoplasmic Reticulum Ca2+ ATPase by Phospholamban},
	journal = {Annual meeting in Biophysical society},
	volume = {106},
	year = {2014},
	month = {01/2014},
	publisher = {Elsevier},
	abstract = {Compelling evidence suggests that reduced sarcoplasmic reticulum (SR) Ca 2+ uptake via\&nbsp;the SR Ca 2+ ATPase (SERCA) is a major contributor to the development of Ca 2+ signaling\&nbsp;abnormalities in heart failure, and equally important as other known contributors to impaired\&nbsp;Ca 2+ handling.},
	author = {Peter M. {Kekenes-Huskey} and Andrew G {Edwards} and Johan Elon {Hake} and Anushka P. {Michailova} and Andrew J. {McCammon} and Andrew D. {McCulloch}}
}
@inbook {Simula.simula.2290,
	title = {Calcium Signaling in Cardiomyocyte Models With Realistic Geometries (6th Edition)},
	booktitle = {Cardiac Electrophysiology: From Cell to Bedside },
	year = {2013},
	month = {2013},
	pages = {33.1-33.10},
	publisher = {Elsevier Science},
	organization = {Elsevier Science},
	edition = {6},
	chapter = {33},
	isbn = {9781455728565},
	author = {Anushka P. {Michailova} and Andrew G {Edwards} and Johan Elon {Hake} and Hoshijima, Masahiko and Andrew D. {McCulloch}},
	editor = {Zipes, Douglas and Jalife, Jose}
}
@article {Simula.simula.2284,
	title = {Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice},
	journal = {Biophysical Journal},
	volume = {105},
	number = {9},
	year = {2013},
	pages = {2130},
	doi = {10.1016/j.bpj.2013.09.020},
	author = {Peter M. {Kekenes-Huskey} and Liao, Tao and Andrew K. {Gillette} and Johan Elon {Hake} and Zhang, Yongjie and Anushka P. {Michailova} and Andrew D. {McCulloch} and Andrew J. {McCammon}}
}
@misc {Simula.simula.1428,
	title = {Modeling Calcium Dynamics in Realistic Rabbit Ventricular Myocytes With Several Transverse Tubules},
	year = {2012},
	author = {Peter M. {Kekenes-Huskey} and Johan Elon {Hake} and Cheng, Yuhui and Michael J. {Holst} and Frank B. {Sachse} and John H. {Bridge} and Andrew D. {McCulloch} and Andrew J. {McCammon} and Anushka P. {Michailova}}
}
@misc {Simula.simula.1410,
	title = {Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit},
	year = {2012},
	author = {Johan Elon {Hake} and Andrew G {Edwards} and Yu, Z. and Peter M. {Kekenes-Huskey} and Anushka P. {Michailova} and Andrew J. {McCammon} and Michael J. {Holst} and Hoshijima, Masahiko and Andrew D. {McCulloch}}
}
@article {Simula.simula.1318,
	title = {Modeling Cardiac Calcium Sparks in a Three-Dimensional Reconstruction of a Calcium Release Unit},
	journal = {The Journal of Physiology},
	volume = {590},
	number = {18},
	year = {2012},
	month = {Sept},
	pages = {4403-4422},
	author = {Johan Elon {Hake} and Andrew G {Edwards} and Yu, Z. and Peter M. {Kekenes-Huskey} and Anushka P. {Michailova} and Andrew J. {McCammon} and Michael J. {Holst} and Hoshijima, Masahiko and Andrew D. {McCulloch}}
}
@article {Simula.simula.1722,
	title = {Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries},
	journal = {Frontiers in Physiology},
	volume = {3},
	year = {2012},
	pages = {351},
	keywords = {Workshop},
	author = {Peter M. {Kekenes-Huskey} and Cheng, Yuhui and Johan Elon {Hake} and Frank B. {Sachse} and John H. {Bridge} and Michael J. {Holst} and Andrew J. {McCammon} and Andrew D. {McCulloch} and Anushka P. {Michailova}}
}
@article {Chen-2012-15002,
	title = {Multi-Scale Continuum Modeling of Biological Processes: From Molecular Electro-Diffusion to Sub-Cellular Signaling Transduction},
	journal = {Computational Science \& Discovery},
	volume = {5},
	number = {1},
	year = {2012},
	pages = {015002},
	keywords = {Conference},
	author = {Cheng, Y. and Peter M. {Kekenes-Huskey} and Johan Elon {Hake} and Michael J. {Holst} and Andrew J. {McCammon} and Anushka P. {Michailova}}
}
@article {Slow-Calcium-Depolarization-Calcium,
	title = {Slow Calcium-Depolarization-Calcium Waves May Initiate Fast Local Depolarization Waves in Ventricular Tissue},
	journal = {Progress in Biophysics and Molecular Biology},
	volume = {110},
	number = {2-3},
	year = {2012},
	month = {July 24},
	pages = {295-304},
	abstract = {Intercellular calcium waves in cardiac myocytes are a well-recognized, if incompletely understood, phenomenon. In a	variety of preparations, investigators have reported multi-cellular calcium waves or triggered propagated contractions, but the	mechanisms of propagation and pathological importance of these events remain unclear. Here, we review existing experimental data and present a computational approach to investigate the mechanisms of multi-cellular calcium wave propagation. Over the past 50 years, the standard modeling paradigm for excitable cardiac tissue	has seen increasingly detailed models of the dynamics of individual cells coupled in tissue solely by intercellular and interstitial current flow. Although very successful, this modeling regime has been unable to capture two important phenomena: 1) the slow intercellular calcium waves observed experimentally, and 2) how intercellular calcium events resulting in delayed after depolarizations at the cellular level could overcome a source-sink mismatch to initiate depolarization waves in tissue. In this paper, we introduce a mathematical model with subcellular spatial resolution, in which we allow both inter- and intracellular current flow and calcium diffusion. In simulations of coupled cells employing this model, we observe: a) slow inter-cellular calcium waves propagating at about 0.1 mm/s, b) faster Calcium-Depolarization-Calcium (CDC) waves, traveling at about 1 mm/s, and c) CDC- waves that can set off fast depolarization-waves (50 cm/s) in tissue with varying gap-junction conductivity.},
	author = {Tveito, Aslak and Glenn T. {Lines} and Andrew G {Edwards} and Maleckar, Molly and Anushka P. {Michailova} and Johan Elon {Hake} and Andrew D. {McCulloch}}
}
@misc {Simula.simula.966,
	title = {Contributions of Multiple T-Tubules and Membrane Ca2+ Flux Localization to Sub-Cellular Ca2+ Signaling in Rabbit Ventricular Myocytes},
	year = {2011},
	author = {Peter M. {Kekenes-Huskey} and Johan Elon {Hake} and Cheng, Yuhui and Sachse, Frank and Bridge, John and Andrew J. {McCammon} and Anushka P. {Michailova}}
}
@misc {Simula.simula.968,
	title = {Contributions of Structural T-Tubule Heterogeneities and Membrane Ca2+ Flux Localization to Local Ca2+ Signaling in Rabbit Ventricular Myocytes},
	year = {2011},
	author = {Peter M. {Kekenes-Huskey} and Johan Elon {Hake} and Cheng, Yuhui and Sachse, Frank and Bridge, John and Andrew J. {McCammon} and Anushka P. {Michailova}}
}
@misc {Simula.simula.964,
	title = {A Stochastic Model of the Ryanodine Receptor Featuring Coupled Gating and Competitive Binding of Luminal and Cytosolic Ca2+ and Mg2+},
	year = {2011},
	author = {Johan Elon {Hake} and William E. {Louch} and Haugen, K. and Sjaastad, Ivar and Ole M. {Sejersted} and Andrew D. {McCulloch} and Anushka P. {Michailova} and Glenn T. {Lines}}
}
@article {Simula.sc.1184,
	title = {Numerical Analysis of Ca2+ Signaling in Rat Ventricular Myocytes With Realistic Transverse-Axial Tubular Geometry and Inhibited Sarcoplasmic Reticulum},
	journal = {PLoS Computational Biology},
	volume = {6},
	number = {10},
	year = {2010},
	pages = {e1000972},
	publisher = {PubMed Central},
	doi = {doi:10.1371/journal.pcbi.1000972},
	author = {Cheng, Y. and Yu, Z. and Hoshijima, M. and Michael J. {Holst} and Andrew D. {McCulloch} and Andrew J. {McCammon} and Anushka P. {Michailova}}
}
@article {Simula.sc.1210,
	title = {Modeling Transmural Heterogeneity of KATP Current in Rabbit Ventricular Myocytes},
	journal = {American Journal of Physiology - Cell Physiology},
	volume = {293},
	number = {2},
	year = {2007},
	pages = {C542-C557},
	author = {Anushka P. {Michailova} and Lorentz, W. and Andrew D. {McCulloch}}
}
