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Search results for biblio_year:2023
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2020
K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch. Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch. "Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere." Archives of Biochemistry and Biophysics 695 (2020): 108582.
2019
Y. Aboelkassem, K. J. McCabe, G. Huber, M. Regnier, A. J. McCammon and A. D. McCulloch. "A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics." Biophysical Journal 117, no. 12 (2019): 2255-2272.
2018
K. J. McCabe, Y. Aboelkassem, S. Dewan, M. Regnier and A. D. McCulloch. A Markov State Model of the Sarcomere to Explain the Effects of dATP on Cardiac Contraction. Biophysical Society 62nd Annual Meeting, San Francisco CA, 2018.
2017
S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch. "Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype." Frontiers in Physiology 14, no. 8 (2017).
2016
S. Dewan, K. J. McCabe, M. Regnier, A. D. McCulloch and S. Lindert. "Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation—An Integrated Multiscale Modeling Study." The Journal of Physical Chemistry B 120, no. 33 (2016): 8264-8275.