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2021
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito. "A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes." PLoS Computational Biology 17 (2021): e1009233.
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito. "From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology." Frontiers in Physiology 12 (2021): 763584.
2020
A. Tveito, K. H. Jæger, M. Maleckar, W. R. Giles and S. Wall. "Computational translation of drug effects from animal experiments to human ventricular myocytes." Nature Scientific Reports (2020): 10537.
2014
J. Koivumäki, R. Clark, D. Belke, C. Kondo, P. Fedak, M. Maleckar and W. R. Giles. "Na+ Current Expression in Human Atrial Myofibroblasts: Its Identity and Functional Consequences." Frontiers in Physiology 5 (2014): 275.
2012
R. A. Rose, D. Belke, M. Maleckar and W. R. Giles. "Ca(2+) Entry Through TRP-C Channels Regulates Fibroblast Biology in Chronic Atrial Fibrillation." Circulation 126 (2012): 2039-2041.
2009
M. Maleckar, J. L. Greenstein, W. R. Giles and N. A. Trayanova. "Electrotonic Coupling Between Human Atrial Myocytes and Fibroblasts Alters Excitability and Repolarization." Biophysical Journal 97 (2009): 2179-2190.PDF icon Simula.SC.448.pdf (986.82 KB)
M. Maleckar, J. L. Greenstein, W. R. Giles and N. A. Trayanova. "K+ Current Changes Account for the Rate Dependence of the Action Potential in the Human Atrial Myocyte." American Journal of Physiology - Heart and Circulatory Physiology 297 (2009): 1398-1410.PDF icon Simula.SC.450.pdf (1.52 MB)
2008
M. Maleckar, J. L. Greenstein, W. R. Giles and N. A. Trayanova. Coupling of Human Atrial Myocytes and Myofibroblasts Can Lead to Conduction Disturbances In HRS Scientific Sessions 2008., 2008.
M. Maleckar, J. L. Greenstein, N. A. Trayanova and W. R. Giles. "Mathematical Simulations of Ligand-Gated and Specific Cell-Type Effects in the Human Atrium." Progress in Biophysics and Molecular Biology 98 (2008): 161-70.
2007
S. N. Flaim, W. R. Giles and A. D. McCulloch. "Arrhythmogenic Consequences of Na+ Channel Mutations in the Transmurally Heterogeneous Mammalian Left Ventricle: Analysis of the I1768V SCN5A Mutation." Heart Rhythm 4 (2007): 768-778.