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M. T. Hock, A. Teitgen, K. J. McCabe, S. P. Hirakis, G. Huber, M. Regnier, R. E. Amaro, A. J. McCammon and A. D. McCulloch

Multiscale computational modeling of the effects of 2’-deoxy-ATP on cardiac muscle calcium handling

Journal of Applied Physics 134, no. 7 (2023).
Journal Article
2023
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V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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V. Timmermann, A. G. Edwards, S. Wall, J. Sundnes and A. D. McCulloch

Arrhythmogenic current generation by myofilament-triggered Ca2+ release and sarcomere heterogeneity

Biophysical Journal 117, no. 12 (2019): 2471-2485.
Journal Article
2019
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18 June 2019
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Viviane Timmermann successfully defended her PhD

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2023

Journal articles

M. T. Hock, A. Teitgen, K. J. McCabe, S. P. Hirakis, G. Huber, M. Regnier, R. E. Amaro, A. J. McCammon and A. D. McCulloch

Multiscale computational modeling of the effects of 2’-deoxy-ATP on cardiac muscle calcium handling

Journal of Applied Physics 134, no. 7 (2023).
Status: Published
2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published
2019

Journal articles

Y. Aboelkassem, K. J. McCabe, G. Huber, M. Regnier, A. J. McCammon and A. D. McCulloch

A Stochastic Multiscale Model of Cardiac Thin Filament Activation Using Brownian-Langevin Dynamics

Biophysical Journal 117, no. 12 (2019): 2255-2272.
Status: Published
Y. Aboelkassem, J. D. Powers, K. J. McCabe and A. D. McCulloch

Multiscale Models of Cardiac Muscle Biophysics and Tissue Remodeling in Hypertrophic Cardiomyopathies

Current Opinion in Biomedical Engineering 11 (2019): 35-44.
Status: Published
K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito

Properties of cardiac conduction in a cell-based computational model

PLoS Computational Biology 15, no. 5 (2019).
Status: Published
J. D. Powers, C. Yuan, K. J. McCabe, J. D. Murray, M. C. Childers, G. V. Flint, F. Moussavi-Harami, S. Mohran, R. Castillo, C. Zuzek et al.

Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin

Proceedings of the National Academy of Sciences (2019).
Status: Published
V. Timmermann, A. G. Edwards, S. Wall, J. Sundnes and A. D. McCulloch

Arrhythmogenic current generation by myofilament-triggered Ca2+ release and sarcomere heterogeneity

Biophysical Journal 117, no. 12 (2019): 2471-2485.
Status: Published
2017

Journal articles

S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

Frontiers in Physiology 14, no. 8 (2017).
Status: Published
V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

An integrative appraisal of mechano-electric feedback mechanisms in the heart

Progress in biophysics and molecular biology 130 (2017): 404-417.
Status: Published