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Most recent publications

V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

Frontiers in Physiology 14, no. 8 (2017).
Journal Article
2017
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V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

An integrative appraisal of mechano-electric feedback mechanisms in the heart

Progress in biophysics and molecular biology 130 (2017): 404-417.
Journal Article
2017
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News

18 June 2019
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Viviane Timmermann successfully defended her PhD

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2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2017

Journal articles

S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

Frontiers in Physiology 14, no. 8 (2017).
Status: Published
V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

An integrative appraisal of mechano-electric feedback mechanisms in the heart

Progress in biophysics and molecular biology 130 (2017): 404-417.
Status: Published

Posters

V. Timmermann, L. A. Dejgaard, A. D. McCulloch, K. H. Haugaa, A. G. Edwards and S. Wall

Role of Electromechanical Feedback in Stretch Induced Arrhythmias : From Single Myocyte to Multicellular Level

Gordon Research Conference on Arrhythmia Mechanisms, Ventura, California, USA, 2017.
Status: Published

Talks, contributed

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. Wall and T. A. Quinn

Integrated Mechanisms of Mechano-Electric feedback in Ischemic Arrhythmogenesis

In Bergen, Norway, 2017.
Status: Published
2009

Journal articles

S. G. Campbell, E. Howard, J. Aguado-Sierra, B. A. Coppola, J. H. Omens, L. J. Mulligan and A. D. McCulloch

Effect of Transmurally Heterogeneous Myocyte Excitation-contraction Coupling on Canine Left Ventricular Electromechanics

Experimental Physiology 94 (2009): 541-552.
Status: Published
J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro

Systems Approaches and Algorithms for Discovery of Combinatorial Therapies

Systems Biology and Medicine 2, no. 2 (2009): 181-193.
Status: Published
J. D. Feala, L. C. Coquin, D. Zhou, G. G. Haddad, G. Paternostro and A. D. McCulloch

Metabolism As Means for Hypoxia Adaptation: Metabolic Profiling and Flux Balance Analysis

BMC Systems Biology 3 (2009): 3-91.
Status: Published