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Most recent publications

V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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S. G. Campbell and A. D. McCulloch

Multi-Scale Computational Models of Familial Hypertrophic Cardiomyopathy: Genotype to Phenotype

Journal of the Royal Society Interface 8, no. 64 (2011).
Journal Article
2011
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E. J. Howard, J. W. Covell, L. J. Mulligan, A. D. McCulloch and J. H. Omens

Improvement in Pump Function With Endocardial Biventricular Pacing Increases With Activation Time at the Left Ventricular Pacing Site in Failing Canine Hearts

American Journal of Physiology - Heart and Circulatory Physiology 301 (2011): H1447-H1455.
Journal Article
2011
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News

18 June 2019
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Viviane Timmermann successfully defended her PhD

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2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2011

Journal articles

S. G. Campbell and A. D. McCulloch

Multi-Scale Computational Models of Familial Hypertrophic Cardiomyopathy: Genotype to Phenotype

Journal of the Royal Society Interface 8, no. 64 (2011).
Status: Published
E. J. Howard, J. W. Covell, L. J. Mulligan, A. D. McCulloch and J. H. Omens

Improvement in Pump Function With Endocardial Biventricular Pacing Increases With Activation Time at the Left Ventricular Pacing Site in Failing Canine Hearts

American Journal of Physiology - Heart and Circulatory Physiology 301 (2011): H1447-H1455.
Status: Published
A. Tveito, G. T. Lines, P. Li and A. D. McCulloch

On Defining Candidate Drug Characteristics for Long-QT

Mathematical Biosciences and Engineering 8 (2011): 861-873.
Status: Published

Posters

J. E. Hake, W. E. Louch, K. Haugen, I. Sjaastad, O. M. Sejersted, A. D. McCulloch, A. P. Michailova and G. T. Lines

A Stochastic Model of the Ryanodine Receptor Featuring Coupled Gating and Competitive Binding of Luminal and Cytosolic Ca2+ and Mg2+

2011.
Status: Published
2009

Journal articles

S. G. Campbell, E. Howard, J. Aguado-Sierra, B. A. Coppola, J. H. Omens, L. J. Mulligan and A. D. McCulloch

Effect of Transmurally Heterogeneous Myocyte Excitation-contraction Coupling on Canine Left Ventricular Electromechanics

Experimental Physiology 94 (2009): 541-552.
Status: Published
J. D. Feala, L. C. Coquin, D. Zhou, G. G. Haddad, G. Paternostro and A. D. McCulloch

Metabolism As Means for Hypoxia Adaptation: Metabolic Profiling and Flux Balance Analysis

BMC Systems Biology 3 (2009): 3-91.
Status: Published
J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro

Systems Approaches and Algorithms for Discovery of Combinatorial Therapies

Systems Biology and Medicine 2, no. 2 (2009): 181-193.
Status: Published