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Most recent publications

V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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S. Morotti, A. G. Edwards, A. D. McCulloch, D. M. Bers and E. Grandi

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII

The Journal of Physiology 592, no. 6 (2014): 1181-1197.
Journal Article
2014
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K. P. Vincent, A. D. McCulloch and A. G. Edwards

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

Frontiers in Pharmacology 5 (2014).
Journal Article
2014
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News

18 June 2019
People

Viviane Timmermann successfully defended her PhD

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2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2018

Posters

Y. Aboelkassem, K. J. McCabe, G. Huber, J. Sundnes and A. D. McCulloch

Turning the Azimuthal Motions of Adjacent Tropomyosins into a Coupled N-body Problem in a Brownian Model of Cardiac Thin Filament Activation

In Biophysical Journal. San Francisco, California/U.S.A.: Elsevier, 2018.
Status: Published
K. J. McCabe, Y. Aboelkassem, S. Dewan, M. Regnier and A. D. McCulloch

A Markov State Model of the Sarcomere to Explain the Effects of dATP on Cardiac Contraction

Biophysical Society 62nd Annual Meeting, San Francisco CA, 2018.
Status: Published

Talks, contributed

V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards

A computational study of the contribution of mechano-electric feedback to arrhythmogenic current generation

In Berlin, Germany. Heart by Numbers, Biophysical Society, 2018.
Status: Published
2014

Journal articles

A. G. Edwards, E. Grandi, J. E. Hake, S. Patel, P. Li, S. Miyamoto, J. H. Omens, J. H. Brown, D. M. Bers and A. D. McCulloch

Non-equilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle

Circulation: Arrhythmia and Electrophysiology 7, no. 6 (2014): 1205-1213.
Status: Published
J. E. Hake, P. M. Kekenes-Huskey and A. D. McCulloch

Computational modeling of subcellular transport and signaling

Current Opinion in Structural Biology 25 (2014): 92-97.
Status: Published
S. Morotti, A. G. Edwards, A. D. McCulloch, D. M. Bers and E. Grandi

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII

The Journal of Physiology 592, no. 6 (2014): 1181-1197.
Status: Published
S. Morotti, A. G. Edwards, A. D. McCulloch, D. M. Bers and E. Grandi

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII

The Journal of physiology 592, no. 6 (2014): 1181-1197.
Status: Published