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Most recent publications

S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

Frontiers in Physiology 14, no. 8 (2017).
Journal Article
2017
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V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

An integrative appraisal of mechano-electric feedback mechanisms in the heart

Progress in biophysics and molecular biology 130 (2017): 404-417.
Journal Article
2017
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J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch

Modeling Cardiac Calcium Sparks in a Three-Dimensional Reconstruction of a Calcium Release Unit

The Journal of Physiology 590 (2012): 4403-4422.
Journal Article
2012
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P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, A. J. McCammon, A. D. McCulloch and A. P. Michailova

Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries

Frontiers in Physiology 3 (2012): 351.
Journal Article
2012
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18 June 2019
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Viviane Timmermann successfully defended her PhD

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2018

Posters

Y. Aboelkassem, K. J. McCabe, G. Huber, J. Sundnes and A. D. McCulloch

Turning the Azimuthal Motions of Adjacent Tropomyosins into a Coupled N-body Problem in a Brownian Model of Cardiac Thin Filament Activation

In Biophysical Journal. San Francisco, California/U.S.A.: Elsevier, 2018.
Status: Published
K. J. McCabe, Y. Aboelkassem, S. Dewan, M. Regnier and A. D. McCulloch

A Markov State Model of the Sarcomere to Explain the Effects of dATP on Cardiac Contraction

Biophysical Society 62nd Annual Meeting, San Francisco CA, 2018.
Status: Published

Talks, contributed

V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards

A computational study of the contribution of mechano-electric feedback to arrhythmogenic current generation

In Berlin, Germany. Heart by Numbers, Biophysical Society, 2018.
Status: Published
2017

Journal articles

S. Dewan, K. J. McCabe, M. Regnier and A. D. McCulloch

Insights and Challenges of Multi-Scale Modeling of Sarcomere Mechanics in cTn and Tm DCM Mutants—Genotype to Cellular Phenotype

Frontiers in Physiology 14, no. 8 (2017).
Status: Published
V. Timmermann, L. A. Dejgaard, K. H. Haugaa, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

An integrative appraisal of mechano-electric feedback mechanisms in the heart

Progress in biophysics and molecular biology 130 (2017): 404-417.
Status: Published

Posters

V. Timmermann, L. A. Dejgaard, A. D. McCulloch, K. H. Haugaa, A. G. Edwards and S. Wall

Role of Electromechanical Feedback in Stretch Induced Arrhythmias : From Single Myocyte to Multicellular Level

Gordon Research Conference on Arrhythmia Mechanisms, Ventura, California, USA, 2017.
Status: Published

Talks, contributed

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. Wall and T. A. Quinn

Integrated Mechanisms of Mechano-Electric feedback in Ischemic Arrhythmogenesis

In Bergen, Norway, 2017.
Status: Published
2012

Journal articles

J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch

Modeling Cardiac Calcium Sparks in a Three-Dimensional Reconstruction of a Calcium Release Unit

The Journal of Physiology 590 (2012): 4403-4422.
Status: Published
P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, A. J. McCammon, A. D. McCulloch and A. P. Michailova

Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries

Frontiers in Physiology 3 (2012): 351.
Status: Published
A. Tveito, G. T. Lines, A. G. Edwards, M. Maleckar, A. P. Michailova, J. E. Hake and A. D. McCulloch

Slow Calcium-Depolarization-Calcium Waves May Initiate Fast Local Depolarization Waves in Ventricular Tissue

Progress in Biophysics and Molecular Biology 110 (2012): 295-304.
Status: Published