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Most recent publications

V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro

Systems Approaches and Algorithms for Discovery of Combinatorial Therapies

Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2 (2010): 93.
Journal Article
2010
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S. G. Campbell, F. V. Lionetti, K. S. Campbell and A. D. McCulloch

Coupling of Adjacent Tropomyosins Enhances Cross-Bridge-Mediated Cooperative Activation in a Markov Model of the Cardiac Thin Filament

Biophysical Journal 98 (2010): 2254-2264.
Journal Article
2010
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18 June 2019
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Viviane Timmermann successfully defended her PhD

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2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2010

Journal articles

S. G. Campbell, F. V. Lionetti, K. S. Campbell and A. D. McCulloch

Coupling of Adjacent Tropomyosins Enhances Cross-Bridge-Mediated Cooperative Activation in a Markov Model of the Cardiac Thin Filament

Biophysical Journal 98 (2010): 2254-2264.
Status: Published
Y. Cheng, Z. Yu, M. Hoshijima, M. J. Holst, A. D. McCulloch, A. J. McCammon and A. P. Michailova

Numerical Analysis of Ca2+ Signaling in Rat Ventricular Myocytes With Realistic Transverse-Axial Tubular Geometry and Inhibited Sarcoplasmic Reticulum

PLoS Computational Biology 6 (2010): e1000972.
Status: Published
J. D. Feala, J. Cortes, P. M. Duxbury, C. Piermarocchi, A. D. McCulloch and G. Paternostro

Systems Approaches and Algorithms for Discovery of Combinatorial Therapies

Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2 (2010): 93.
Status: Published
J. G. Jacot, H. Kita-Matsuo, K. A. Wei, H. S. V. Chen, J. H. Omens, M. Mercola and A. D. McCulloch

Cardiac Myocyte Force Development During Differentiation and Maturation

Annals of the New York Academy of Sciences 1188 (2010): 121-127.
Status: Published
J. H. Omens, A. D. McCulloch and L. J. Mulligan

Ventricular Dilation and Electrical Dyssynchrony Synergistically Increase Regional Mechanical Non-Uniformity But Not Mechanical Dyssynchrony: a Computational Model

Circulation: Heart Failure 3 (2010): 528-536.
Status: Published
J. H. Omens, A. D. McCulloch and L. J. Mulligan

Ventricular Dilation and Electrical Dyssynchrony Synergistically Increase Regional Mechanical Non-Uniformity But Not Mechanical Dyssynchrony; a Computational Model

Circulation: Heart Failure 3 (2010): 528-536.
Status: Published
A. Zemljic-Harpf, R. S. Ross, L. R. Frank, A. D. McCulloch and J. H. Omens

Determination of Three-Dimensional Ventricular Strain Distributions in Gene-Targeted Mice Using Tagged MRI

Magnetic Resonance in Medicine 64, no. 5 (2010): 1281-1288.
Status: Published