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Most recent publications

V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, A. J. McCammon, A. D. McCulloch and A. P. Michailova

Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries

Frontiers in Physiology 3 (2012): 351.
Journal Article
2012
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A. Tveito, G. T. Lines, A. G. Edwards, M. Maleckar, A. P. Michailova, J. E. Hake and A. D. McCulloch

Slow Calcium-Depolarization-Calcium Waves May Initiate Fast Local Depolarization Waves in Ventricular Tissue

Progress in Biophysics and Molecular Biology 110 (2012): 295-304.
Journal Article
2012
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18 June 2019
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Viviane Timmermann successfully defended her PhD

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2020

Journal articles

K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Status: Published
V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Status: Published

Talks, contributed

K. J. McCabe, Y. Aboelkassem, A. Teitgen, M. Regnier and A. D. McCulloch

Multiscale modelling determines mechanisms of action for 2'-deoxy-ATP, a myosin activating therapeutic for heart failure

In VPH 2020, Paris, France (Virtual). VPH 2020, 2020.
Status: Published
2012

Journal articles

J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch

Modeling Cardiac Calcium Sparks in a Three-Dimensional Reconstruction of a Calcium Release Unit

The Journal of Physiology 590 (2012): 4403-4422.
Status: Published
P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, A. J. McCammon, A. D. McCulloch and A. P. Michailova

Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes With Realistic T-Tubule Geometries

Frontiers in Physiology 3 (2012): 351.
Status: Published
A. Tveito, G. T. Lines, A. G. Edwards, M. Maleckar, A. P. Michailova, J. E. Hake and A. D. McCulloch

Slow Calcium-Depolarization-Calcium Waves May Initiate Fast Local Depolarization Waves in Ventricular Tissue

Progress in Biophysics and Molecular Biology 110 (2012): 295-304.
Status: Published

Posters

A. G. Edwards, J. E. Hake, J. H. Brown and A. D. McCulloch

βAR-Stimulation Causes EADs But Not DADs in Pre-Failure CAMKIIδC Transgenic Myocytes

In Biophysical Society annual meeting, 2012.
Status: Published
J. E. Hake, A. G. Edwards, Z. Yu, P. M. Kekenes-Huskey, A. P. Michailova, A. J. McCammon, M. J. Holst, M. Hoshijima and A. D. McCulloch

Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit

2012.
Status: Published
P. M. Kekenes-Huskey, J. E. Hake, Y. Cheng, M. J. Holst, F. B. Sachse, J. H. Bridge, A. D. McCulloch, A. J. McCammon and A. P. Michailova

Modeling Calcium Dynamics in Realistic Rabbit Ventricular Myocytes With Several Transverse Tubules

2012.
Status: Published
2006

Journal articles

P. N. Costandi, L. R. Frank, A. D. McCulloch and J. H. Omens

Role of Diastolic Properties in the Transition to Failure in a Mouse Model of Cardiac Dilatation

American Journal of Physiology - Heart and Circulatory Physiology 291 (2006): H2971-2979.
Status: Published