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Most recent publications

M. T. Hock, A. Teitgen, K. J. McCabe, S. P. Hirakis, G. Huber, M. Regnier, R. E. Amaro, A. J. McCammon and A. D. McCulloch

Multiscale computational modeling of the effects of 2’-deoxy-ATP on cardiac muscle calcium handling

Journal of Applied Physics 134, no. 7 (2023).
Journal Article
2023
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A. G. Edwards, J. van den Brink and A. D. McCulloch

Calcium Signaling in Cardiomyocyte Models With Realistic Geometries

In Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 362-375. 8th ed. Vol. 1. Elsevier, 2021.
Book Chapter
2021
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V. Timmermann and A. D. McCulloch

Mechano-electric coupling and arrhythmogenic current generation in a computational model of coupled myocytes

Frontiers in physiology 11 (2020): 1573.
Journal Article
2020
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K. J. McCabe, Y. Aboelkassem, A. Teitgen, G. Huber, A. J. McCammon, M. Regnier and A. D. McCulloch

Predicting the effects of dATP on cardiac contraction using multiscale modeling of the sarcomere

Archives of Biochemistry and Biophysics 695 (2020): 108582.
Journal Article
2020
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2017

Talks, contributed

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. Wall and T. A. Quinn

Integrated Mechanisms of Mechano-Electric feedback in Ischemic Arrhythmogenesis

In Bergen, Norway, 2017.
Status: Published
2016

Journal articles

S. Dewan, K. J. McCabe, M. Regnier, A. D. McCulloch and S. Lindert

Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation—An Integrated Multiscale Modeling Study

The Journal of Physical Chemistry B 120, no. 33 (2016): 8264-8275.
Status: Published
S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

Journal of Molecular and Cellular Cardiology 96 (2016): 63-71.
Status: Published
A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch

Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states

Mathematical Biosciences 277 (2016): 126-135.
Status: Published

Posters

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

Role of Electromechanical Feedback in Mitral Valve Prolapse Arrhythmia

Freiburg, Germany: Conference on Cardiac Mechano-Electric Couping and Arrhythmias, 2016.
Status: Published
2015

Journal articles

S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

Journal of Molecular and Cellular Cardiology In Press (2015).
Status: Published
K. P. Vincent, M. J. Gonzales, A. K. Gillette, C. T. Villongco, S. Pezzuto, J. H. Omens, M. J. Holst and A. D. McCulloch

High-order finite element methods for cardiac monodomain simulations

Frontiers in Physiology (2015).
Status: Published
B. L. de Oliveira, J. Sundnes, S. Wall and A. D. McCulloch

Increased Membrane Capacitance Is the Dominant Mechanism of Stretch-Dependent Conduction Slowing in the Rabbit Heart: a Computational Study

Cellular and Molecular Bioengineering 8, no. 2 (2015): 237-246.
Status: Published

Posters

S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Ranolazine Prevents Phase-3 Early Afterdepolarizations in Human Atrial Myocytes by Inhibiting Na Current Non-Equilibrium Reactivation

In Biophysical Society annual meeting. Elsevier, 2015.
Status: Published
2014

Journal articles

A. G. Edwards, E. Grandi, J. E. Hake, S. Patel, P. Li, S. Miyamoto, J. H. Omens, J. H. Brown, D. M. Bers and A. D. McCulloch

Non-equilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle

Circulation: Arrhythmia and Electrophysiology 7, no. 6 (2014): 1205-1213.
Status: Published