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V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Journal Article
2022
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X. Zhang, C. E. R. Smith, S. Morotti, A. G. Edwards, D. Sato, W. E. Louch, H. Ni and E. Grandi

Mechanisms of spontaneous Ca<sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: II Ca<sup>2+</sup>‐handling protein variation

The Journal of Physiology 116 (2022).
Journal Article
2022
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X. Zhang, H. Ni, S. Morotti, C. E. R. Smith, D. Sato, W. E. Louch, A. G. Edwards and E. Grandi

Mechanisms of spontaneous Ca <sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse‐axial tubule variation

The Journal of Physiology (2022).
Journal Article
2022
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W. E. Louch, H. Perdreau-Dahl and A. G. Edwards

Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?

Frontiers in Physiology 13 (2022).
Journal Article
2022
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26 August 2016
Alessio Buccino from the Summer School tests the waters of San Diego. Photo: Christopher Villongco, UCSD

Report from the Summer School in Computational Physiology

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2017

Talks, contributed

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch, S. Wall and T. A. Quinn

Integrated Mechanisms of Mechano-Electric feedback in Ischemic Arrhythmogenesis

In Bergen, Norway, 2017.
Status: Published
2016

Journal articles

S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

Journal of Molecular and Cellular Cardiology 96 (2016): 63-71.
Status: Published
A. Tveito, G. T. Lines, A. G. Edwards and A. D. McCulloch

Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states

Mathematical Biosciences 277 (2016): 126-135.
Status: Published

Book chapters

A. G. Edwards, J. E. Hake, A. P. Michailova, M. Hoshijima and A. D. McCulloch

Calcium Signaling in Cardiomyocyte Models With Realistic Geometries (7th Edition)

In Cardiac Electrophysiology: From Cell to Bedside. 7th ed. Elsevier Science, 2016.
Status: Accepted

Posters

V. Timmermann, A. G. Edwards, J. Sundnes, A. D. McCulloch and S. Wall

Role of Electromechanical Feedback in Mitral Valve Prolapse Arrhythmia

Freiburg, Germany: Conference on Cardiac Mechano-Electric Couping and Arrhythmias, 2016.
Status: Published
2015

Journal articles

S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

Journal of Molecular and Cellular Cardiology In Press (2015).
Status: Published
M. J. Shattock, M. Ottolia, D. M. Bers, M. P. Blaustein, A. Boguslavskyi, ii, J. Bossuyt, J. H. B. Bridge, Y. Chen-Izu, C. E. Clancy and A. G. Edwards

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

The Journal of Physiology 593, no. 6 (2015): 1361-1382.
Status: Published

Posters

S. Morotti, A. D. McCulloch, D. M. Bers, A. G. Edwards and E. Grandi

Ranolazine Prevents Phase-3 Early Afterdepolarizations in Human Atrial Myocytes by Inhibiting Na Current Non-Equilibrium Reactivation

In Biophysical Society annual meeting. Elsevier, 2015.
Status: Published
A. H. Ottesen, C. R. Carlson, A. G. Edwards, O. J. B. Landsverk, R. Johansen, M. K. Moe, M. Bjøraas, M. Stridsberg, T. Omland, G. Christensen et al.

Secretoneurin, a Novel Endogenous CaMKII Inhibitor, Augments Cardiomyocyte Calcium Handling and Inhibits Arrhythmogenic Calcium Release

In Biophysical Journal. Vol. 108. Elsevier, 2015.
Status: Published
2014

Journal articles

A. G. Edwards, E. Grandi, J. E. Hake, S. Patel, P. Li, S. Miyamoto, J. H. Omens, J. H. Brown, D. M. Bers and A. D. McCulloch

Non-equilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle

Circulation: Arrhythmia and Electrophysiology 7, no. 6 (2014): 1205-1213.
Status: Published