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V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Journal Article
2022
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X. Zhang, C. E. R. Smith, S. Morotti, A. G. Edwards, D. Sato, W. E. Louch, H. Ni and E. Grandi

Mechanisms of spontaneous Ca<sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: II Ca<sup>2+</sup>‐handling protein variation

The Journal of Physiology 116 (2022).
Journal Article
2022
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X. Zhang, H. Ni, S. Morotti, C. E. R. Smith, D. Sato, W. E. Louch, A. G. Edwards and E. Grandi

Mechanisms of spontaneous Ca <sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse‐axial tubule variation

The Journal of Physiology (2022).
Journal Article
2022
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W. E. Louch, H. Perdreau-Dahl and A. G. Edwards

Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?

Frontiers in Physiology 13 (2022).
Journal Article
2022
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22 February 2018
A California beach

Summer School in Computational Physiology open for applicants

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Export 74 results:
2019

Journal articles

V. Timmermann, A. G. Edwards, S. Wall, J. Sundnes and A. D. McCulloch

Arrhythmogenic current generation by myofilament-triggered Ca2+ release and sarcomere heterogeneity

Biophysical Journal 117, no. 12 (2019): 2471-2485.
Status: Published

Talks, contributed

V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards

A one-dimensional computational study of mechano-electric feedback and arrhythmogenic current generation

In Gordon Research Conference "Cardiac Arrhythmia Mechanisms", Barga, Italy, 2019.
Status: Published
2018

Journal articles

T. R. Kolstad, J. van den Brink, N. MacQuaide, P. K. Lunde, M. Frisk, J. M. Aronsen, E. S. Norden, A. Cataliotti, I. Sjaastad, O. M. Sejersted et al.

Ryanodine Receptor Dispersion Disrupts Ca2+-Release in Failing Cardiac Myocytes

eLife 7 (2018): e39427.
Status: Published
T. Mäki-Marttunen, F. Krull, F. Bettella, E. Hagen, S. Næss, T. V. Ness, T. Moberget, T. Elvs\aashagen, C. Metzner, A. Devor et al.

Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations

Cerebral Cortex 29 (2018): 875-891.
Status: Published
A. Tveito, K. H. Jæger, N. Huebsch, B. Charrez, A. G. Edwards, S. Wall and K. E. Healy

Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems

Nature Scientific Reports 8 (2018).
Status: Published
M. Vagos, I. G. M. van Herck, J. Sundnes, H. Arevalo, A. G. Edwards and J. Koivumäki

Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

Frontiers in Physiology 9 (2018): 1221.
Status: Published
I. van Herck, B. H. Bentzen, V. Seutin, H. Arevalo, M. Maleckar, N. V. Marrion and A. G. Edwards

Model development of sk channel gating incorporating calcium sensitivity and drug interaction

Biophysical Journal 114 (2018): 306a.
Status: Published

Posters

I. G. M. van Herck, B. H. Bentzen, V. Seutin, J. Koivumäki, M. Maleckar, N. V. Marrion and A. G. Edwards

In silico Model of Gating Kinetics, Temperature Dependence and Calcium Sensitivity of the SK Channel

Biophysical Society Thematic Meeting: The Heart by Numbers, 2018.
Status: Published
I. G. M. van Herck, B. H. Bentzen, V. Seutin, H. Arevalo, M. Maleckar, N. V. Marrion and A. G. Edwards

Model development of SK channel gating incorporating calcium sensitivity and drug interaction

Biophysical Society 62nd Annual Meeting, San Francisco CA, 2018.
Status: Published

Talks, contributed

V. Timmermann, J. Sundnes, S. Wall, A. D. McCulloch and A. G. Edwards

A computational study of the contribution of mechano-electric feedback to arrhythmogenic current generation

In Berlin, Germany. Heart by Numbers, Biophysical Society, 2018.
Status: Published