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K. H. Jæger and A. Tveito

Efficient, cell-based simulations of cardiac electrophysiology; The Kirchhoff Network Model (KNM)

npj Systems Biology and Applications 9 (2023): 25.
Journal Article
2023
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K. H. Jæger and A. Tveito

Differential Equations for Studies in Computational Electrophysiology

Simula SpringerBriefs on Computing: Springer, 2023.
Book
2023
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K. H. Jæger, E. Ivanovic, J. P. Kucera and A. Tveito

Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

PLoS Computational Biology 19, no. 2 (2023): e1010895.
Journal Article
2023
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V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Journal Article
2022
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02 January 2023
Deputy Director Kyrre Lekve (Photo: Simula/Bård Gudim)

Kyrre Lekve is Interim Managing Director

Simula in the media

18 March 2016

Suksessrike Simula vil stå på egne ben - sier nei til å bli del av Universitetet i Oslo

Simula på Fornebu er et av Norges mest suksessrike forskningsmiljøer. Sterke krefter vil slå senteret sammen med Universitetet i Oslo (UiO) og flytte det til Blindern. Men det vil ikke Simula.
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2021

Journal articles

K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito

Efficient numerical solution of the EMI model representing the extracellular space (E), cell membrane (M) and intracellular space (I) of a collection of cardiac cells

Frontiers in Physics 8 (2021): 579461.
Status: Published
K. H. Jæger, V. Charwat, S. Wall, K. E. Healy and A. Tveito

Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems

Frontiers in Pharmacology 11 (2021): 569489.
Status: Published

Book chapters

K. H. Jæger and A. Tveito

Derivation of a Cell-Based Mathematical Model of Excitable Cells

In Modeling Excitable Tissue: The EMI Framework, 1-13. Vol. 7. Cham: Springer International Publishing, 2021.
Status: Published
K. H. Jæger, K. G. Hustad, X. Cai and A. Tveito

Operator Splitting and Finite Difference Schemes for Solving the EMI Model

In Modeling Excitable Tissue: The EMI Framework, 44-55. Vol. 7. Cham: Springer International Publishing, 2021.
Status: Published
2020

Journal articles

K. H. Jæger, V. Charwat, B. Charrez, H. Finsberg, M. Maleckar, S. Wall, K. E. Healy and A. Tveito

Improved computational identification of drug response using optical measurements of human stem cell derived cardiomyocytes in microphysiological systems

Frontiers in Pharmacology 10 (2020).
Status: Published
A. Tveito, K. H. Jæger, M. Maleckar, W. R. Giles and S. Wall

Computational translation of drug effects from animal experiments to human ventricular myocytes

Nature Scientific Reports (2020): 10537.
Status: Published
2019

Journal articles

A. P. Buccino, M. Kuchta, K. H. Jæger, T. V. Ness, P. Berthet, K. Mardal, G. Cauwenberghs and A. Tveito

How does the presence of neural probes affect extracellular potentials?

Journal of Neural Engineering 16 (2019): 026030.
Status: Published
K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito

Properties of cardiac conduction in a cell-based computational model

PLoS Computational Biology 15, no. 5 (2019).
Status: Published
K. H. Jæger, S. Wall and A. Tveito

Detecting undetectables: Can conductances of action potential models be changed without appreciable change in the transmembrane potential?

Chaos 29 (2019).
Status: Published

Posters

Å. Telle, B. Charrez, K. E. Healy, A. Tveito and S. Wall

A numerical model of mechanical properties of cardiac tissue in heart-on-a-chip devices

Norwegian meeting on PDEs, Trondheim, Norway, 2019.
Status: Published