Safety assurance and certification are amongst the most expensive and time-consuming tasks in the development of safety-critical embedded systems. The increasing complexity and size of this kind of systems combined with the growing market demand requires the industry to implement a coherent reuse strategy. A major problem arises as typically a safetycritical product and accompanying safety evidence is monolithic, based on the whole product, and evolutions to the product become costly and time consuming because they entail regenerating the entire evidence-set. Another key difficulty appears when trying to reuse products from one application domain in another, because they are constrained by different standards and the full safety assurance certification process is applied as for a new product, thus reducing the return on investment of such reuse decision.