| Authors | J. L. Bruse, K. S. Mcleod, G. Biglino, H. N. Ntsinjana, C. Capelli, T. Hsia, M. Sermesant, X. Pennec, A. Taylor and S. Schievano |
| Title | A Non-parametric Statistical Shape Model for Assessment of the Surgically Repaired Aortic Arch in Coarctation of the Aorta: How Normal is Abnormal? |
| Afilliation | Scientific Computing, Scientific Computing, Scientific Computing |
| Status | Published |
| Publication Type | Proceedings, refereed |
| Year of Publication | 2015 |
| Conference Name | Statistical Atlases and Computational Modeling of the Heart (STACOM 2015) |
| Edition | MICCAI Workshop |
| Date Published | 10/2015 |
| Publisher | Lecture Notes in Computer Science, Springer. Verlag |
| Keywords | Aortic Arch, Coarctation of the Aorta, Mathematical Currents, Non-parametric Statistical Shape Model, Partial Least Square Regression |
| Abstract | Coarctation of the Aorta (CoA) is a cardiac defect that re- quires surgical intervention aiming to restore an unobstructed aortic arch shape. Many patients suffer from complications post-repair, which are commonly associated with arch shape abnormalities. Determining the degree of shape abnormality could improve risk stratification in recom- mended screening procedures. Yet, traditional morphometry struggles to capture the highly complex arch geometries. Therefore, we use a non- parametric Statistical Shape Model based on mathematical currents to fully account for 3D global and regional shape features. By comput- ing a template aorta of a population of healthy subjects and analysing its transformations towards CoA arch shape models using Partial Least Squares regression techniques, we derived a shape vector as a measure of subject-specific shape abnormality. Results were compared to a shape ranking by clinical experts. Our study suggests Statistical Shape Mod- elling to be a promising diagnostic tool for improved screening of complex cardiac defects. |
| Notes | Oral Presentation - Jan L. Bruse |
| Citation Key | 23826 |