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V. Charwat, B. Charrez, B. A. Siemons, H. Finsberg, K. H. Jæger, A. G. Edwards, N. Huebsch, S. Wall, E. Miller, A. Tveito et al.

Validating the Arrhythmogenic Potential of High-, Intermediate-, and Low-Risk Drugs in a Human-Induced Pluripotent Stem Cell-Derived Cardiac Microphysiological System

ACS Pharmacology & Translational Science 5, no. 8 (2022): 652-667.
Journal Article
2022
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X. Zhang, C. E. R. Smith, S. Morotti, A. G. Edwards, D. Sato, W. E. Louch, H. Ni and E. Grandi

Mechanisms of spontaneous Ca<sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: II Ca<sup>2+</sup>‐handling protein variation

The Journal of Physiology 116 (2022).
Journal Article
2022
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X. Zhang, H. Ni, S. Morotti, C. E. R. Smith, D. Sato, W. E. Louch, A. G. Edwards and E. Grandi

Mechanisms of spontaneous Ca <sup>2+</sup> release‐mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse‐axial tubule variation

The Journal of Physiology (2022).
Journal Article
2022
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W. E. Louch, H. Perdreau-Dahl and A. G. Edwards

Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?

Frontiers in Physiology 13 (2022).
Journal Article
2022
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2021

Journal articles

A. F. Iseppe, H. Ni, S. Zhu, X. Zhang, R. Coppini, P. Yang, U. Srivatsa, C. E. Clancy, A. G. Edwards, S. Morotti et al.

Sex‐Specific Classification of Drug‐Induced Torsade de Pointes Susceptibility Using Cardiac Simulations and Machine Learning

Clinical Pharmacology & Therapeutics 1105970708108167, no. 2 (2021): 380-391.
Status: Published
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes

PLoS Computational Biology 17 (2021): e1009233.
Status: Published
K. H. Jæger, A. G. Edwards, W. R. Giles and A. Tveito

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology

Frontiers in Physiology 12 (2021): 763584.
Status: Published

Book chapters

A. G. Edwards, J. van den Brink and A. D. McCulloch

Calcium Signaling in Cardiomyocyte Models With Realistic Geometries

In Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 362-375. 8th ed. Vol. 1. Elsevier, 2021.
Status: Published
2020

Journal articles

B. Charrez, V. Charwat, B. Siemons, H. Finsberg, E. Miller, A. G. Edwards and K. E. Healy

In Vitro Safety “Clinical Trial” of the Cardiac Liability of Hydroxychloroquine and Azithromycin as COVID19 Polytherapy

Clinical Pharmacology & Therapeutics (2020).
Status: Published
T. Mäki-Marttunen, N. Iannella, A. G. Edwards, G. T. Einevoll and K. T. Blackwell

A unified computational model for cortical post-synaptic plasticity

eLife 9 (2020).
Status: Published

Posters

X. Shen, T. R. Kolstad, J. van den Brink, M. Frisk, Y. Hou, E. Norden, A. G. Edwards, I. Sjaastad, C. Soeller and W. E. Louch

3D Dstorm Imaging Reveals Camkii-Dependent Dispersal of Ryanodine Receptor Clusters in Failing Rat Cardiomyocytes

In Biophysical Journal. Biophysical Journal: Cell Press, 2020.
Status: Published
2019

Journal articles

K. H. Jæger, A. G. Edwards, A. D. McCulloch and A. Tveito

Properties of cardiac conduction in a cell-based computational model

PLoS Computational Biology 15, no. 5 (2019).
Status: Published
T. Mäki-Marttunen, T. Kaufmann, T. Elvs\aashagen, A. Devor, S. Djurovic, L. T. Westlye, M. Linne, M. Rietschel, D. Schubert, S. Borgwardt et al.

Biophysical Psychiatry—How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders

Frontiers in psychiatry 10 (2019).
Status: Published
X. Shen, J. van den Brink, Y. Hou, D. Colli, C. Le, T. R. Kolstad, N. MacQuaide, C. R. Carlson, P. M. Kekenes-Huskey, A. G. Edwards et al.

3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes

The Journal of Physiology 597, no. 2 (2019): 399-418.
Status: Published